Influence of personality traits on incidence rate and severity of atherosclerotic cardiovascular disease of patients from senior age group

Investigation of interconnection between IHD, peculiarities of psychological status of people from senior age groups and the level of stress hormone in blood allowed singling out two psychological types. Stress hormones depend-ing on the special features of the psychological type indirectly determine the specific form of reaction to stress leading to IHD. All cases of painful forms of IHD among representatives of the I psychological type manifested second to stable stenocardia, among representatives of the II psychological type – more often by the painless form of myocardial infarction, in most cases flowing as a Qwave myocardial infarction. Alcohol plays a major role in the development of IHD. Depression as a reflection of stresshormone level disorder can be viewed as a marker of unfavorable flow of blood circulation pathology.

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Influence of psychological personality traits of elderly patients on the incidence, severity and dynamics of coronary heart disease

Research of the relationship between the characteristics of psychological portrait of elderly patients by Cattell, coronary heart disease (CHD), the dynamics and the level of stress hormones in the blood allowed to distinguish three psycho types. Stress hormones, depending on the characteristics of psychological status of patients indirectly cause a peculiar form of reaction to stress, contributing to formation of some circulatory disease, particularly coronary heart disease. All cases of painful forms of ischemic heart disease among I
type representatives manifest stable effort angina, in II psycho – most painless form of myocardial infarction, which in most cases takes the form of Q-wave myocardial infarction. Alcohol plays an important role in the development of CHD. Accompanying CHD depression, being a reflection of violations of stress hormones proportion, can be considered as a marker of unfavourable flow of cardiovascular disease.

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Personality types and somatic dysfunction in elderly patients

We identified three personality types of elderly patients among the participants of the study. These types were associated
with different reaction to stress that induced somatic dysfunction, mainly coronary artery disease. In 60% of
individuals with the 1st psychotype stress was associated with high levels of catecholamines and glucocorticoids.
Among the patients with the 2nd psychotype, 95.4% did not demonstrate any increase in the level of hormones. In the
group of patients with the 3rd psychotype, 53.4% developed unfavourable reactions to stress, including long-term elevation
of hormone levels, frequent cases of myocardial infarction and arterial hypertension, failure of adaptation, anxiety,
and depression.

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Stress and state of the immune system in norm and pathology. Brief review of literature

Sympathoadrenal and hypothalamic-pituitary-adrenal structures form the basis of a stress-responsive system that secretes stress hormones, epinephrine, noradrenaline and cortisol, interacting with receptors of the nervous, endocrine and immune cells, including granulocytes. In the first minutes of acute stress, the leukocytes activated by hormones get into the bloodstream and are redistributed to different compartments of the organism, selectively accumulating in tissues subjected to stressor aggression and stimulate immune responses. Chronic stress initially activates and further inhibits the immune response through changes in secretion by immunocytes of proinflammatory and anti-inflammatory cytokines. Due to immunosuppression, the body develops disease states with the outcome of a specific somatic pathology.

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