Medical experts’ opinion on organizing specialized medical aid for children with epilepsy and convulsive disorders in zabaykalsky krai

Goal of the research is to assess medical and social factors in the system of organizing medical aid for children with epilepsy in Zabaykalsky Krai with the participation of medical experts. Research methods and data: questionnaire data from 24 medical experts in Zabaykalsky Krai was analyzed. Findings. According to the medical experts, condition of specialized medical aid for patients with epilepsy and convulsive disorders in Zabaykalsky Krai at the present time based on compliance with the standard of care (100,0 %) and availability of drugs in chemists shops (95,8%) appears satisfactory and good. According to the medical experts, the weakest spot of the current organization of medical aid is interaction with social services (33,3%, low estimate). Epileptologist’s consultation is necessary in all cases; otolaryngologist’s consultation is the least needed by the patients (54,2 %, low estimate). Additional diagnostic techniques, which are needed by the greater part of the patients: electroencephalography (EEG) (95,8%), plain brain magnetic resonance imaging (MRI) (91,7%). The medical experts consider conducting regular long-term antiepileptic therapy the most significant arrangement (87,5%) among those necessary to improve treatment outcomes and to improve the quality of life of patients with epilepsy. Conclusion. According to the medical experts, the current organization of specialized medical aid for children with epilepsy and convulsive disorders in Zabaykalsky Krai based on compliance with the standard of care and availability of drugs is good and satisfactory. Condition of interaction of the organization of specialized medical aid with social services has been evaluated as unsatisfactory. The medical experts consider epileptologist the most essential specialist in the context of treatment for children with epilepsy and convulsive disorders. Demand for comprehensive treatment (incl. consultations of neurologist, epileptologist and psychiatrist) amounts to 20,84 %. Regular longterm antiepileptic medication is the basic arrangement for improvement of treatment outcomes and improvement of the quality of life of children with epilepsy and convulsive disorders.

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Genetic traits of teenage abdominal obesity in the city of samara

Metabolic syndrome is a group of metabolic risk factors including dyslipidemia, carbohydrate intolerance, arterial hypertension and abdominal obesity. It is known that leptin participates in energy homeostasis. The object of the work was to study leptin concentration and biochemical values in obese and normal and to identify the relation of leptin receptor gene (LEPR) Gln223Arg polymorphism to blood leptin concentration and metabolic disorders in Samara school children. The methods were as follows: the study was carried out among 125 students (including 100 obese children and 25 normal children who were a control group). The indices which were studied are leptin,
insulin, glucose and lipid values. LEPR Gln223Arg genotyping was performed using the method of polymerase chain reaction. The results were as follows: The obese children had higher leptin values in their blood serum than the children of the control group (р < 0,01). There were found out significant correlations of LEPR Gln223Arg
polymorphism with the leptin and glucose values (p < 0,05). The obese group also had more frequent cases of LEPR polymorphism than the control group did. (p < 0,05).
The conclusion: the results of the study show that leptin values correlate with metabolic disorders. LEPR Gln223Arg polymorphism influenced the leptin concentration. Thus it can provoke metabolic disorders in Samara students.

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The level of ionized calcium in the oral fluid of children with chronic generalized catarrhal gingivitis and bronchial asthma

Comprehensive assessment of biochemical parameters of calcium-phosphorus metabolism is a part of a new approach for optimizing the prevention and treatment of periodontal disease in patients with low bone mineral density and high risk of osteopenic syndrome.
We examined 120 children aged 7–12 years with chronic generalized catarrhal gingivitis and bronchial asthma. The diagnosis of gingivitis was established using main and additional diagnostic methods. Children with generalized catarrhal gingivitis and bronchial asthma were found to have low levels of Ca2+ in theiroral fluid. We evaluated the dynamics of Ca2+ concentration depending on the severity of bronchial asthma. The lowest level of Ca2+ was observed in patients with moderate persistent asthma. The treatment scheme that includes bioresonance stimulation + ‘Biol’ + ‘Calcemin’ improves this parameter. Thus, the results of biochemical examinations suggest that regular comprehensive treatment of chronic generalized catarrhal gingivitis in patients with bronchial asthma using physical factors, the solution (extract) of sulfide mud of the Saki Lake, osteotropic drug, and a mouthwash stimulates the saturation of oral fluid with calcium ions and prevents the inflammation.

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