All Posts in Category: Medical Herald №026-2017

Electrocardiographic features of butane inhalation

Due to the wide spread of smoking and accessories for it, many adolescents all over the world inhale gas lighter refills (butane), which is called ‘sniffing’. People inhaling butane may suddenly die, often during some activity. Butane is an inhaled recreational drug that sensitises the myocardium to arrhythmogenic effects of catecholamines. Experiments with rats showed arrhythmogenic and ischemic effects associated with inhalation of butane.

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Health and quality of life of children and adolescents in saratov region: monitoring and management

We identified specific features of health, quality of life, and development of hygienic activity in urban and rural schoolchildren residing on the territory of the region and city. We analysed deviant activity and behavioural risk factors associated with poor self-rated health. We revealed an increase in the number of children with some abnormalities: by 8.9% among urban schoolchildren and by 12.8% among rural schoolchildren.

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Cultural paradigm of professional education: current trends

The article contains the analysis of the professional education system in terms of psychological and pedagogical studies. Cultural paradigm of professional education is currently considered as a priority model of education. We identified the relationship between professional education and culture, as well as its impact on the formation of the future professionals.

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Current problems of health care delivery and rehabilitation of patients with stoma

There is a significant increase in the colorectal cancer incidence in recent years. Treatment of colorectal cancer often requires either permanent or temporary colostomy. Presence of stoma implies significant limitations for a person. Complications after surgery associated with stoma formation are a substantial problem for many patients. Organisation of special healthcare facilities for patients with stoma will allow returning these people to their usual life and ensure their rapid postoperational adaptation. World experience
demonstrates that specially trained nurses can provide adequate rehabilitative care for patients with stoma. The possibility of obtaining this assistance in the immediate vicinity of patient’s place of residence creates comfortable conditions for a patient. It prevents the development of complications and reduces possible additional expenditure for their treatment.

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The use of cardiointervalography in the examination of temporary disability in patinets with primary and repeated brain concussion

Traumatic brain injury is an relevant problem nowadays. Objective: to improve the diagnosis of mild traumatic
brain injury through the investigation of heart rate variability in order to objectify autonomic disorders. Materials and
methods: we examined 140 patients with traumatic brain injury during the acute period using cardiointervalography.
Results: our results suggest that cardiointervalography helps to identify autonomic dysfunction in patients with mild
traumatic brain injury and normalisation of functions in response to therapy.

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Processing of the data on the condition of patient’s immune system

Synchronisation in the processing of the data of immunological examination of a patient performed at different time-points using the program ‘Immunologist’. It allows to control the dynamics of the disease and the correctness of treatment (including immunocorrective therapy). The program helps to perform effective outpatient monitoring.

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Surgical treatment of patients during the acute period of ischemic stroke

We analysed the results of 56 reconstructive surgeries of the carotid arteries during the acute period of ischemic stroke in 55 patients who underwent treatment in the Division of Cardiovascular Surgery at the Samara City Clinical Hospital No. 1 named after N.I. Pirogov between June 2015 and August 2016. Surgical intervention was performed 1–18 days post ischemic stroke onset. Neurological status was assessed using the USA National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS). Before surgery, 18 patients demonstrated neurological deficit of 4 points according to the mRS. Carotid endarterectomy (CEA) was performed in 55 patients; of them 25 patients underwent eversion carotid endarterectomy (eCEA). Ten patients simultaneously underwent eCEA and resection of the internal carotid artery in the case of stenosis and tortuosity. One patient underwent eCEA and carotid-subclavian bypass grafting. CEA with application of autovenous patch in the common carotid artery (CCA) and internal carotid artery (ICA) was performed in 8 patients. Reconstructive surgery of the external carotid artery (ECA) with the resection of occlusional ICA was performed in 7 patients. ICA resection complicated by pathological tortuosity was performed in 2 patients. By the moment of discharge 46 (83 %) of participants had a regression of neurological symptoms. Of them, 9 (20 %) demonstrated complete recovery of neurological deficit, whereas 2 (4 %) had increased neurological deficit. Two patients died during the postoperative period: one of them 24 days post surgery due to increasing respiratory and heart failure, another one – 29 days post surgery due to increasing renal and heart failure. No recurrent strokes were observed in both cases (according to autopsy results). Surgical interventions during the first 18 days after the development of ischemic stroke facilitates the regression of neurological deficit in most of the cases; they are safe in terms of hemorrhagic transformation development if the surgery is performed in a special vascular center.

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Wound healing prognosis using the integral hematologic indexes

The article presents a study which aims to determine the prognosis of wound healing using the integral hematologic indexes. The study was devoted to the assessment of the integral hematologic indexes in rats with wounds to predict the outcome of the wound process. The study included 297 albino male rats weighing 190–210 g. The rats were divided into 3 groups (99 rats in each): control group, rats with a modelled wound process and abdominal wall tension, and rats with a modelled wound process with the use of transplant. During the experiment we estimated the following integral hematologic indexes: Krebs index, Bredeck index, leukocyte index, neutrophils/monocytes ratio, lymphocytes/monocytes ratio, lymphocytes/eosinophils ratio, albumin/globulin ratio, oxyproline coefficient. Our results suggest that changes in integral hematologic indexes in rats were mostly statistically and clinically significant. Thus, we can conclude that pathophysiological features of the blood reactions under various conditions (modelling of wound healing) are crucial in both specific and non-specific protective reaction of the organism affecting its resistance and reactivity and, therefore, determining the course and the outcome of wound healing.

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Comparison of the efficacy of apixaban monotherapy and its combination with fraxiparin in patients with acute deep vein thrombosis of the lower limbs complicated by pulmonary embolism with low risk of death

We compared the efficacy of apixaban monotherapy and apixaban combined with fraxiparin in patients with deep vein thrombosis of the lower limbs complicated by pulmonary embolism with low risk of death. We found that recanalisation of the lower limb veins and the vessels of the pulmonary circuit is more pronounced in patients treated with apixaban in combination with fraxiparin.

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