All Posts in Category: Medical Herald №024-2017

Features of the background electroencephlogram type with indicators of medium amplitude in adolescents

The background values of the electroencephalogram based on the mean amplitude in adolescents are analyzed. It is pointed out that the background indicators of the amplitude are determined not only by the age of the subjects, but also by the emotiveness of the information obtained in advance. Different terms for the formation of the amplitude of alpha rhythm in boys and girls are revealed, which points to the need to take into account the emotional coloring of information given to boys and girls.

The asymmetry coefficient confirms the opinion about the specific involvement of the right hemisphere in the identification of emotionally colored objects. It was found that the negative coloring of information in children aged 11-13 leads to depression of the α-rhythm.


Peculiarities of surgical assistance to population in part of execution of operations on organs of abdominal cavity, skin and subcutaneous cell

The article is based on the official statistics of the Ministry of Health of the Russian Federation and contains an analysis of the performance of operations on the organs of the abdominal cavity, skin and subcutaneous tissue, in dynamics over 5 years. The present study also contains an analysis of the feverish complications after performing operations from 2011 to 2015.


Organization of the quality management system with laboratory information systems in medical organizations

The implementation of a quality management system in laboratory medicine is the most important solution for any organization, since its application will help improve the effectiveness of the organization and increase customer satisfaction. The organization of a quality management system is a phased and lengthy process, in order to achieve a positive result, active introduction of modern information systems is required. Various commercial laboratory information systems are considered in the work from the position of the possibility of their implementation in clinical diagnostic laboratories as a quality management system. It is determined that all modern information systems meet the requirements of implementing a quality management system in medical laboratories.


Actual trends of private health sector development: Russian and foreign experience

The article examines the main world and Russian trends in the development of private medicine. With the appearance of private property, competition, market conditions of management in Russia, entrepreneurs increasingly began to pay attention to the social sphere of services, including health care. But many of them do not take into account the low profitability of the industry and the high social responsibility of business, forming the basis of negative examples. Complex socio-economic conditions, a wave of crises also have a negative impact on the formation of the private health sector. Issues of state support for this segment of the market are becoming more urgent.


Features of remodeling of the left ventricle in patients who have suffered myocardial infarction during chronic heart insufficiency formation

The article assesses the morphofunctional changes in the left ventricle of the heart in patients who underwent myocardial infarction with the development of chronic heart failure. 100 patients with myocardial infarction with chronic heart failure of stage I of the functional class II by NYHA (group 1) and chronic heart failure IIa of stage II of the functional class of NYHA (group 2) were examined. With the help of computer echocardiography in all patients, the morphofunctional parameters of the left ventricle were evaluated depending on the severity of chronic heart failure. With Stage I Stage II CHF. According to NYHA, the growth of both linear indices (ICRR by 15.5% (p = 0.0004), ICDD by 32.3% (p = 0.0004) and volume indices – by 40% (p = 0.00075 ), ICSI by 106.2% (p = 0.00067) of LV parameters. Along with this, an increase in IMI was detected by 31.7% (p = 0.0004), and also by 98% (0.00002) of IH and a 13.9% increase in LR (p = 0.02). The ejection fraction, the shortening fraction, and the rate of shortening of the circular fibers of the myocardium were significantly decreased with respect to control by 24% (p = 0.001), 22% (P = 0.02) and 16% (p = 0.03), respectively, but remained generally within the normal range. Violation of filling processes was noted mainly in a non-restrictive manner. In the 2nd group there was a further increase in LV linear and volume parameters, but there was no proportional thickening of its walls: the OTC index decreased significantly both in comparison with the norm by 19.4% (p = 0.02) and with the value in the group 1 at 21.6% (p = 0.045), the hypertrophy index – with 1 group at 13% (p = 0.01), the ratio of BWW / MM ml / g increased to 0.77 ml / g (in the control 0.63 Ml /
g). Among the pathological types of filling, the amount of restrictive variant increased. It was established that with stage I CHF, I fc NYHA in patients who underwent MI, mainly compensatory hypertrophy and LV dilatation is formed without significant violations of its contractile function. Violation of the process of LV filling by a non-restrictive type predominates. Development of CHF IIa of stage II f. Is accompanied by a progressive expansion of the LV cavity without proportional wall thickening, a decrease in the effectiveness of systolic contraction, an increase in myocardial stress, an increase in the severity of diastolic disorders with predominance of a prognostically unfavorable restrictive type of filling. Violation of the LV filling process precedes its systolic dysfunction.


Stress and state of the immune system in norm and pathology. Brief review of literature

Sympathoadrenal and hypothalamic-pituitary-adrenal structures form the basis of a stress-responsive system that secretes stress hormones, epinephrine, noradrenaline and cortisol, interacting with receptors of the nervous, endocrine and immune cells, including granulocytes. In the first minutes of acute stress, the leukocytes activated by hormones get into the bloodstream and are redistributed to different compartments of the organism, selectively accumulating in tissues subjected to stressor aggression and stimulate immune responses. Chronic stress initially activates and further inhibits the immune response through changes in secretion by immunocytes of proinflammatory and anti-inflammatory cytokines. Due to immunosuppression, the body develops disease states with the outcome of a specific somatic pathology.


Possibility of development of preeclampsia in clinically healthy women

Psychophysiological criteria for the possibility of developing of preeclampsia in women with uncomplicated pregnancy are cardiovascular type of self-regulation of blood circulation, the predominant influence of the parasympathetic department of the autonomic nervous system on hemodynamics, disruption in the adaptive capabilities of the body, increased heart rate and increased DBP, the presence of a hypertensive -prenuations in character traits, an increase in the level of neuroticism.


Comparison of effectiveness of thrombolitical and anticoagulant therapy in patients with thromboembolia of pulmonary artery of medium-high risk of death

We compared the efficiency of thrombolytic and anticoagulant therapy in patients with pulmonary thromboembolia of pulmonary artery of the medium-high risk of death. It has been established that anticoagulant therapy is not inferior to thrombolytic therapy in the recanalization of blood vessels of the small circulation, but the effect from it develops more slowly.


Forecasting the development of cancer of prostate. Multidisciplinary approach

Differential diagnosis of prostate cancer (PCa) and benign prostatic hyperplasia (BPH) is an urgent and complex problem of outpatient urology. The evaluation of the level of prostate-specific antigen (PSA) is considered by many urologists as the “gold” standard for screening PCa. However, it is not always possible to establish the diagnosis of prostate cancer reliably, which often leads to hyperdiagnosis and an increase in the number of unnecessary prostate biopsies.

We conducted a retrospective analysis of 122 patients who were on the screening for prostate cancer. All patients were divided into two groups: the main group – 59 (48.3%) men with verified PCa and control group – 63 (51.7%) patients with benign prostatic hyperplasia (BPH).

First, we conducted a comparative analysis of many factors: age, weight, bad habits, testosterone level, prostatespecific antigen (PSA) level, concomitant pathology, blood group, Rh factor, digital rectal examination, ultrasound results of the prostate. Further, using the general models of discriminant analysis, we identified the five most significant risk factors for prostate cancer. Finally, we made a statistical calculation of the prognosis for the development of PCa with the help of binary logistic regression.

Clinical results of the study were histologically confirmed by morphological study. According to the indications, we performed biopsy of the prostate, followed by a study of micro-preparations.