All Posts in Category: Medical Herald №013-2014

Multifunctional biofeedback in optimization of wrestlers’ functional condition

Multifunctional biofeedback using the parameters of respiratory and cardiovascular systems makes it possible to adjust physiological processes, form relationships between several functions, enhance or weaken the control of voluntary and involuntary responses, change their rhythmological structure. This method aims at mobilizing the reserve capacity of the organism through training and increasing the plasticity of regulatory mechanisms.

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Expert questions in rehabilitation

The article describes in detail the problems associated with a process of issuance and formalization of sick certificates for patients directed to health resort treatment. Procedures of formalization and issuance of sick certificates for a period of health resort treatment are regulated by the order of The Ministry of Health of the Russian Federation dated 29.06.2011 № 624n “About approval of the procedures for sick certificates issuance”. However, in practice we often face challenges concerning application of certain order provisions, particularly: when a medical committee of the health resort should make a decision on prolongation and issuance of a sick certificate for patients required additional treatment in specialized health centers immediately after hospital treatment and health resort treatment in tuberculosis health centers? The provisions of the Article 59 of the Federal Law dated 21.11.2011 № 323- FZ “About the basis of health protection in the Russian Federation”, limiting the period of sick certificate prolongation upon the medical committee decision from 30 to 15 calendar days when patients are directed to health resort treatment are also need to be clarified. The author passes his personal opinion on some controversial issues.

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Direct results of treatment for open injuries of spleen

The study analyzed the nearest postoperative period in 30 patients with open injuries of spleen. The main cause of open injuries of spleen was stab and incised abdominal wounds. The following surgeries were used for open injuries of spleen: splenectomy in 15 (50%) patients, splenectomy with autolientransplantation in 8 (26.6 %) cases; organ preservation surgeries with laser technologies were managed to be used in 7 (23.3 %) cases. Analysis of the nearest postoperative period in patients operated for open injuries of spleen revealed that complications developed in 25 (83.3 %) cases. Analysis of the reasons of post-operative complications showed that its development depended on associated injuries, but not on the nature of the surgery. In the nearest postoperative period death was recorded in 9 (30 %) patients.

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Improving the methods to relief postoperative pain in war veterans in intensive care system

The article describes the methods to relief postoperative pain in war veterans in intensive care system. It was determined that relief of postoperative pain should be started before the pain is occurred using intramuscular administration of NSAIDs (ketonal, 100 mg) immediately after admission to ICU and then on routine basis every 8-12 hours, and concomitant use of paracetamol 1 g 2-3 times a day. Relief of postoperative pain in war veterans should be carried out under compulsory monitoring of hemodynamic parameters, heart rate variability, respiration, gas exchange, and in case of opioid analgesics administration, pulse oximetry is also mandatory. Proposed tactics of pain syndrome control in war veterans improves the quality of postoperative analgesia through high level of safety and promotes early postoperative adaptation.

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Dynamics of plasma antioxidant activity indexes in physiological and complicated first trimester of pregnancy

The article decribes the dynamics of ceruloplasmin concentrations and total antioxidant activity of blood plasma in the first trimester of pregnancy in case of physiological gestation course and gestation course complicated by threatened miscarriage. It has been established that after pregnancy incoming the parameters of blood antioxidant activity increase on 62 – 81% as compared to non-pregnant women. Threatened miscarriage is characterized by decline of ceruloplasmin levels and total antioxidant activity of blood plasma.

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Changes of the immune system in squamous cell carcinoma patients during surgical treatment

Changes of the immune status were found in 39 patients with squamous cell carcinoma. Patients’ age was 65 ± 3 years. In all patients, the disease stage was T1-2N0M0. Investigations were conducted prior to the surgery, on the first postoperative day, and then on the fifth, seventh, tenth postoperative days, and 18 months after the surgery. Obtained data were compared with the parameters of cell-mediated immunity from 17 relatively healthy volunteers of the same age and sex (control group 1) and 20 patients operated for skin fibroma (control group 2), age and sex of the patients from the control group 2 matched the main group, the parameters were studied on the same day. The study determined that cell-mediated immunity of squamous cell carcinoma patients before surgical treatment was characterized by decrease in both relative and absolute number of lymphocytes bearing receptors CD16+, CD3+, CD4+, CD8+, and it significantly increased on the tenth postoperative day. In humoral immunity of squamous cell carcinoma patients a decrease of IgG, M amounts, as well as the total amount of complement, its C3 and C4 fractions, TNFa, IL1β, IL-6, IL-10, INFγ, PI, phagocytic coefficient, СТ-сп., СТ-ст were revealed, while amount of CIC was increased. Partial restoration of IgG, M occurs on the tenth postoperative day.

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Morphology of connective tissue in rats cervix at reparative regeneration after experimental tension

The article decribes a study of connective tissue morphology in rats’ uterine cervix at reparative regeneration after experimental tension. It has been established that mechanical experimental tension of lower uterin segment leads to fibers tension, and on the 21st day of regeneration the fibers are fragmented, which may be the result of damage and collagenolysis caused by collagenase from inflammatory cells. Collagen proteolysis induced by various cells plays important role in regulation of collagen type composition in the process of inflammation and regeneration. Whatever is the type of regenerative process after traumatic damage of uterine cervix tissues, the fragmented collagen fibers can not perform their biomechanical function normaly as architectonics is broken.

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Histological examination of the tissue components in a wall of human vagina

The results of light microscopy study, immunohistochemistry with monoclonal antibodies to different specific markers, method of tissue alkaline dissociation and preparation of isolated cells and morphometric analysis considerably completed information regarding the histophysiologic structure of the tissues in a wall of human vagina. The study defined immunohistochemical profile of different collagen types of vaginal connective tissue, proved existence of two muscle tissue types in a wall of the vagina, as well as confirmed positive expression of estrogen receptors not only in epithelial cells but also in leiomyocytuses and stromal cells.

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