Vascular tissue ratio-the lower third esophagus in the prenatal human ontogenesis

Full article

Based on morphological analysis of vascular tissue studied the relationship in the lower third of the esophagus human fetuses of different gestation periods. It is established that the blood supply of the esophagus – gastric passage differs pronounced variability angioarchitectonics, mezhsosudistye overlap zone formed intramural blood plexus and intermuscular adventitial layer.

Bibliography:
  1. Петрова М.Б. Сравнительная оценка структуры мышечной оболочки пищевода рыб и млекопитающих //Морфология. 2001. № 2. С.56-59.
  2. Delattre JF, Avisse C, Marcus C, Flament JB. Functional anatomy of the gastroesophageal junction.Surg Clin North Am,2000;80:241-260.
  3. Granderath F. A., Kamolz Th., Pointner R. (Eds.) Gastroesophageal Reflux Disease. Principles of Disease, Diagnosis, and Treatment. Springer-Verlag/Wien, 2006 -324 р.
  4. Ходасевич Л.С., Гольдберг О.А., Лелявина Т.И., Сисенкова А.Ю., Скворцов М.Б. Особенности клинико-морфологической диагностики и хирургического лечения осложненных форм гастроэзофагеальной рефлюксной болезни // Архив патологии. 2007. № 6. С.7-10.
  5. Котив Б.Н., Кулагин В.И., Василевский Д.И., Силантьев Д.С. Принципы хирургического лечения гастроэзо-фагеальной рефлюксной болезни и антирефлюксные механизмы реконструкций пищеводно-желудочного перехода // Вестник хирургии им. И.И. Грекова. 2011. № 4. С.111-114.
  6. Vandenplas Y, Goyvaerts H, Helven R (1991) Gastroesophageal relfux, as measured by 24-hour pH-monitoring, in 509 healthy infants screened for sudden infant death syndrome. Pediatrics 88: 834-840.
  7. Colletti RB, Di Lorenzo C (2003) Overview of pediatric gastroesophageal reflux disease and proton pump inhibitor therapy. J Pediatr Gastroenterol Nutr 37 (Suppl 1): S7-S11.
  8. Hu FZ, Preston RA, Post JC et al (2000) Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14. JAMA 284: 325–334.
  9. Orenstein SR, Shalaby TM, Finch R et al (2002) Autosomal dominant infantile gastroesophageal reflux disease: exclusion of a 13q14 locus in five well characterized families. Am J Gastroenterol 97:2725–2732.
  10. Liu J., Parashar V., Mittal R.K. Asymmetry of the lower esophageal sphincter pressure: is it related to the muscle thickness or shape of the lower esophageal sphincter? Am. J. Physiol.,1997;272:G1509–G1517.
  11. Davidson G (2003) The role of lower esophageal sphincter function and dysmotility in gastroesophageal reflux in premature infants and in the first year of life. J Pediatr Gastroenterol Nutr 37 (Suppl 1): S17–S22.
  12. Goldani HA, Fernandes MI, Vicente YA et al (2002) Lower esophageal sphincter reacts against intraabdominal pressure in children with symptoms of  gastroesophageal reflux. Dig Dis Sci 47: 2544-2548.
  13. Pandolfino J.E., Shi G., Curry J., Joehl R.J, Brasseur JG, Kahrilas PJ. Esophagogastric junction distensibility: a factor contributing to sphincter incompetence. Am J Physiol,2002;282:G1052–G1058.|
  14. Pandolfino J.E, Bianchi L.K., Lee T.J, Hirano I., Kahrilas P.J. Esophagogastric junction morphology predicts susceptibility to exercise-induced reflux. Am J Gastroenterol., 2004;99:1430-1436.
  15. Маев И. В., Вьючнова Е. С., Щекина М. И. Гастроэзофагеальная рефлюксная болезнь //Лечащий Врач. 2004. № 4. С.14-17.
About the authors

  • P.A. Gelashvili
  • Medical Institute «Reaviz», 443001, Samara, st. Chapaevskaya, 227, doctor of medical sciences, professor, professor of morphology and pathology department

  • V.N.Tokarev
  • Samara Medical Institute «REAVIZ» 443001, Samara, st. Chapaevskaya, 227, postgraduate student, department of morphology and pathology, e-mail : mail@reaviz.ru